Can Bacteria Cause Cancer

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Can Bacteria Cause Cancer

Author : David J. Hess
ISBN : 9780814735626
Genre : Health & Fitness
File Size : 56.30 MB
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Documents the work of alternative cancer researchers--which, the author charges, has been ignored or suppressed by the medical establishment--on a possible link between bacteria and cancer and on alternative treatments for the disease. UP.
Category: Health & Fitness

Bacteria And Cancer

Author : Abdul Arif Khan
ISBN : 9789400725843
Genre : Medical
File Size : 62.75 MB
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Bacterial infections cause substantial morbidity and mortality in cancer patients. These infections always remained enigmatic due to initial reluctance of cancer researchers in understanding their etiologic potential. Etiological association of bacteria with cancer gained credibility after discovery of carcinogenic potential of Helicobacter pylori. Moreover, other suspected associations including Salmonella typhi and gallbladder cancer, Streptococcus bovis and colon cancer, Chlamydia psittaci and ocular adnexal lymphoma and Chlamydia pneumoniae with lung cancer, etc. are looking for a legitimate appraisal to unravel their etiologic potential without prejudice. In contrary, bacteria also show protective role in certain types of cancer. Certain agents derived from bacteria are successfully in practice for the management of cancer. The integrate association of bacteria and cancer is evident in both positive and negative aspects. The role of bacteria in cancer etiology and treatment is vigorously studied since last few years. Present book tries to provide current status of research undergoing in above direction, with the glimpses of future possibility for using microbiological knowledge in the management of this deadly killer. This book will interest specialists dealing with cancer associated infectious complications, researchers working in the field of cancer biology, teachers and scientists in the field of microbiology, biotechnology, medicine and oncology. The unique coverage of bacteriology and cancer association in both positive and negative way can usher into development of novel thrust area for microbiology students and experts.
Category: Medical

Can Bacteria Cause Cancer

Author : David J. Hess
ISBN : 9780814735619
Genre : Health & Fitness
File Size : 68.55 MB
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Documents the work of alternative cancer researchers--which, the author charges, has been ignored or suppressed by the medical establishment--on a possible link between bacteria and cancer and on alternative treatments for the disease. UP.
Category: Health & Fitness

New Weapons To Control Bacterial Growth

Author : Tomas G. Villa
ISBN : 9783319283685
Genre : Science
File Size : 90.51 MB
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Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.
Category: Science

Cancer Unnecessary

Author : Tore Patrick Störtebecker
ISBN : CHI:22499376
Genre : Cancer
File Size : 61.76 MB
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Category: Cancer

Evaluating Alternative Cancer Therapies

Author : David J. Hess
ISBN : 0813525942
Genre : Medical
File Size : 54.70 MB
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At least half a million American cancer patients are using complementary and alternative medicine therapies such as dietary programmes, supplements, imagery and herbs, but little has been done to evaluate these therapies or to provide information about them to the public. As North American cancer rates in recent decades have risen so that a person's lifetime risk is now over one in three, the questions that patients and clinicians have about alternative treatments have continued to grow. How can patients and clinicians make sense of the various options?
Category: Medical

Inflammation Infection And Microbiome In Cancers

Author : Jun Sun
ISBN : 9783030679514
Genre : Medical
File Size : 90.29 MB
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This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
Category: Medical

Microbiome And Cancer

Author : Erle S. Robertson
ISBN : 9783030041557
Genre : Medical
File Size : 82.73 MB
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This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.
Category: Medical

Catching Cancer

Author : Claudia Cornwall
ISBN : 1442215216
Genre : Health & Fitness
File Size : 26.21 MB
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Explores the controversial idea that cancer can be caught, examining the proposed viral and bacterial causes of the disease and how it might be prevented.
Category: Health & Fitness

Bacteria And Cancer

Author : J. Jeljaszewicz
ISBN : UOM:39015006700747
Genre : Medical
File Size : 26.95 MB
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Category: Medical

Drug Resistance In Bacteria Fungi Malaria And Cancer

Author : Gunjan Arora
ISBN : 9783319486833
Genre : Medical
File Size : 68.39 MB
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This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.
Category: Medical

Infectious Complications Of Cancer

Author : J. Klastersky
ISBN : 9781461312390
Genre : Medical
File Size : 61.85 MB
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Despite the major developments in the therapeutic armamentarium for the treatment of infection, the morbidity and mortality of this complication remains very high in patients with compromised defences. Cancer and its treatment represents a major predisposing condition to a variety of infections. These adverse events are still with us, in spite of much progress in the therapy of infectious disease, since cancer therapy is becoming more aggressive, yet further lowering the host's capacity to cope with infections. Moreover, the pathogens adapt effectively to drugs, and at a pace that might outrun industry's capability to produce new agents. Finally, new pathogens are appearing as a consequence of both selection and severe immunosuppression. Infection is so common among cancer patients that its diagnosis and management represent a daily challenge to all oncologists, who must continually strive to keep abreast of developments in the area. The present comprehensive review of the most crucial and challenging aspects of the infectious complications in cancer patients will help them to do just that.
Category: Medical

Plague Time

Author : Paul W. Ewald
ISBN : 9780684869001
Genre : Medical
File Size : 84.97 MB
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A noted biologist defends his controversial thesis that most of our worst killers--including heart disease, cancer, and diabetes--are in fact caused by infectious diseases.
Category: Medical

Viruses More Friends Than Foes Revised Edition

Author : Karin Moelling
ISBN : 9789811224768
Genre : Science
File Size : 30.50 MB
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Coronavirus, AIDS, and Ebola: Viruses are normally defined as pathogens. Most viruses are, however, not enemies or killers. Well-known virologist and cancer researcher Karin Moelling describes surprising insights about a completely new and unexpected world of viruses. Viruses are ubiquitous, in the oceans, our environment, in animals, plants, bacteria, in our body, even in our genomes. They influence our weather, can contribute to control obesity, and can surprisingly be applied against threatening multi-resistant bacteria. The success story of the viruses started more than 3.5 billion years ago in the dawn of life when even cells did not exist. They are the superpower of life. There are more viruses on earth than stars in the sky. Viruses are everywhere. Some of them are incredibly ancient. Many viruses are hundredfold smaller than bacteria, but others are tenfold bigger and they were discovered only recently — the giant viruses, even deep within the permafrost where they were reactivated after 30,000 years.The author talks about a completely new world of viruses, which are based on the most recent, in part her own research results. Could viruses have been our oldest ancestors? Have viruses even 'invented' social behavior, do they lead to geniuses such as Mozart or Einstein — or alternatively to cancer? They can help to cure cancer. In this book, the author made a clear distinction between what is fact and what is her vision. This book is written for a general audience and not just for the experts. Its aim is to stimulate thinking, and perhaps to attract more young scientists to enter this field of research.This revised edition is brought up to date by a new chapter on the SARS-CoV-2 pandemic.
Category: Science

Infectious Agents Associated Cancers Epidemiology And Molecular Biology

Author : Qiliang Cai
ISBN : 9811057648
Genre : Medical
File Size : 21.16 MB
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This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers. Cancer is one of the most common causes of death and diseases in human populations, and 15%-25% of human cancers in worldwide are considered to result from chronic infection by pathogens. Most oncology textbooks address genetic mutation, but not infectious agents such as viruses, bacteria and parasites. As such this book stimulates further research in the new area between cancers and chronic infection, and discusses the epidemiology and molecular biology of infectious causes of cancers. It also explores the prevention and treatment of infection-related cancers, and brings pathogenic research to the forefront in the never-ending endeavor to understand how pathogens maneuver and negotiate in a complex environment, including the micro/macro- environment of the human host. Further, it highlights the urgent need for a concerted program to develop vaccines and other diagnosis and interventions that will eventually help prevent and treat infectious cancers, and decrease their burden on human populations. It offers graduate students and researchers a comprehensive overview of the infectious causes of cancers.
Category: Medical

Bird Keeping As A Source Of Lung Cancer And Other Human Diseases

Author : Peter A.J. Holst
ISBN : 9783642763427
Genre : Medical
File Size : 72.77 MB
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Birdkeeping is becoming increasingly popular, but could it threaten good health? This book discusses the evi- dence suggesting that keeping pet birds is a strong risk factor for lung cancer. Its relation to a number of other endpoints, including death before age 60 and spontaneous abortion, is also examined. In addition, the book looks at the diseases that can be transmitted from birds to man - a fairly unknown field in general medicine. For instance, birds are a source of airborne particles that can cause allergic reactions in humans. People who keep birds as pets tend to have a higher incidence of shortness of breath, colds, sore throats and other flu-like symptoms than those in households without birds. The evidence presented in this book is the result of a ten-year general practice survey. Some recommendations for future research are given.
Category: Medical

Summary The Cancer Code A Revolutionary New Understanding Of A Medical Mystery By Dr Jason Fung The Mw Summary Guide

Author : The Mindset Warrior
ISBN :
Genre : Health & Fitness
File Size : 86.51 MB
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An Easy to Digest Summary Guide... ★☆BONUS MATERIAL AVAILABLE INSIDE★☆ The Mindset Warrior Summary Guides provide you with a unique summarized version of the core information contained in the full book, along with the essentials you need in order to fully comprehend and apply. Maybe you've read the original book, but you'd like a reminder of the core principles? ✅ Maybe you haven't read the book, but want a short summary to save time? ✅ Maybe you'd just like a summarized version to refer to in the future? ✅ In any case, The Mindset Warrior Summary Guides can provide you with just that. Inside You'll Learn: - What makes cancer so ruthless... - Why treatment doesn't always work... - Why lifestyle matters more than genetics in cancer... prevention (and what changes you can make)... - How cancer stays dormant for decades, and what finally activates it... - What we're just now learning about cancer—despite decades and billions of dollars devoted to research... Let's get Started. Download Your Book Today... NOTE: To Purchase "The Cancer Code" (full book); which this is not, simply type the name of the book in the search bar of your bookstore.
Category: Health & Fitness

Magnetic Nanosensors For Multiplexed Bacterial Pathogenesis Identification

Author : Charalambos Kaittanis
ISBN : OCLC:681964465
Genre : Nanoparticles
File Size : 53.29 MB
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Developing diagnostic modalities that utilize nanomaterials and miniaturized detectors can have an impact in point-of-care diagnostics. Diagnostic systems that (i) are sensitive, robust, and portable, (ii) allow detection in clinical samples, (iii) require minimal sample preparation yielding results quickly, and (iv) can simultaneously quantify multiple targets, would have a great potential in biomedical research and public healthcare. Bacterial infections still cause pathogenesis throughout the world (Chapter I). The emergence of multi-drug resistant strains, the potential appearance of bacterial pandemics, the increased occurrence of bacterial nosocomial infections, the wide-scale food poisoning incidents and the use of bacteria in biowarfare highlight the need for designing novel bacterial-sensing modalities. Among the most prominent disease-causing bacteria are strains of Escherichia coli, like the E. coli O157:H7 that produces the Shiga-like toxin (Stx). Apart from diarrheagenic E. coli strains, others cause disease varying from hemolytic uremic syndrome and urinary tract infections to septicemia and meningitis. Therefore, the detection of E. coli needs to be performed fast and reliably in diverse environmental and clinical samples. Similarly, Mycobacterium avium spp. paratuberculosis (MAP), a fastidious microorganism that causes Johne's disease in cattle and has been implicated in Crohn's disease (CD) etiology, is found in products from infected animals and clinical samples from CD patients, making MAP an excellent proof-of-principle model. Recently, magnetic relaxation nanosensors (MRnS) provided the first applications of improved diagnostics with high sensitivity and specificity. Nucleic acids, proteins, viruses and enzymatic activity were probed, yet neither large targets (for instance bacterial and mammalian cells) nor multiple bacterial disease parameters have been simultaneously monitored, in order to provide thorough information for clinical decision making. Therefore, the goal of this study was to utilize MRnS for the sensitive identification of multiple targets associated with bacterial pathogenesis, while monitoring virulence factors at the microorganism, nucleic acid and virulence factor levels, to facilitate improved diagnosis and optimal treatment regimes. To demonstrate the versatility of MRnS, we used MAP as our model system, as well as several other pathogens and eukaryotic cell lines. In initial studies, we developed MRnS suitable for biomedical applications (Chapter II). The resulting MRnS were composed of an iron oxide core, which was caged within a biodegradable polymeric coating that could be further functionalized for the attachment of molecular probes. We demonstrated that depending on the polymer used the physical and chemical properties of the MRnS can be tailored. Furthermore, we investigated the role of polymer in the enzyme-mimicking activity of MRnS, which may lead to the development of optimized colorimetric in vitro diagnostic systems such as immunoassays and small-molecule-based screening platforms. Additionally, via facile conjugation chemistries, we prepared bacterium-specific MRnS for the detection of nucleic acid signatures (Chapter III). Considering that MAP DNA can be detected in clinical samples and isolates from CD patients via laborious isolation and amplification procedures requiring several days, MRnS detected MAP's IS900 nucleic acid marker up to a single MAP genome copy detection within 30 minutes. Furthermore, these MRnS achieved equally fast IS900 detection even in crude DNA extracts, outperforming the gold standard diagnostic method of nested Polymerase Chain Reaction (nPCR). Likewise, the MRnS detected IS900 with unprecedented sensitivity and specificity in clinical isolates obtained from blood and biopsies of CD patients, indicating the clinical utility of these nanosensors. Subsequently, we designed MRnS for the detection of MAP via surface-marker recognition in complex matrices (Chapter III). Milk and blood samples containing various concentrations of MAP were screened and quantified without any processing via MRnS, obtaining dynamic concentration-dependent curves within an hour. The MAP MRnS were able not only to identify their target in the presence of interferences from other Gram positive and Gram negative bacteria, but could differentiate MAP among other mycobacteria including Mycobacterium tuberculosis. In addition, detection of MAP was performed in clinical isolates from CD patients and homogenized tissues from Johne's disease cattle, demonstrating for the first time the rapid identification of bacteria in produce, as well as clinical and environmental samples. However, comparing the unique MAP quantification patterns with literature-available trends of other targets, we were prompted to elucidate the underlying mechanism of this novel behavior (Chapter IV). We hypothesized that the nanoparticle valency--the amount of probe on the surface of the MRnS --may have modulated the changes in the relaxation times ([delta]T2) upon MRnS--target association. To address this, we prepared MAP MRnS with high and low anti-MAP antibody levels using the same nanoparticle formulation. Results corroborated our hypothesis, but to further bolster it we investigated if this behavior is target-size-independent. Hence utilizing small-molecule- and antibody-carrying MRnS, we detected cancer cells in blood, observing similar detection patterns that resembled those of the bacterial studies. Notably, a single cancer cell was identified via high-valency small-molecule MRnS, having grave importance in cancer diagnostics because a single cancer cell progenitor in circulation can effectively initiate the metastatic process. Apart from cells, we also detected the Cholera Toxin B subunit with valencly-engineered MRnS, observing similar to the cellular targets' diagnostic profiling behavior. Finally, as bacterial drug resistance is of grave healthcare importance, we utilized MRnS for the assessment of bacterial metabolism and drug susceptibility (Chapter V). Contrary to spectophotometric and visual nanosensors, their magnetic counterparts were able to quickly assess bacterial carbohydrate uptake and sensitivity to antibiotics even in blood. Two MRnS-based assay formats were devised relying on either the Concanavalin A (Con A)-induced clustering of polysaccharide-coated nanoparticles or the association between free carbohydrates and Con A-carrying MRnS. Overall, taking together these results, as well as those on pathogen detection and the recent instrumentation advancements, the use of MRnS in the clinic, the lab and the field should be anticipated.
Category: Nanoparticles

Infectious Agents Associated Cancers Epidemiology And Molecular Biology

Author : Qiliang Cai
ISBN : 9789811057656
Genre : Medical
File Size : 20.46 MB
Format : PDF, Docs
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This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers. Cancer is one of the most common causes of death and diseases in human populations, and 15%-25% of human cancers in worldwide are considered to result from chronic infection by pathogens. Most oncology textbooks address genetic mutation, but not infectious agents such as viruses, bacteria and parasites. As such this book stimulates further research in the new area between cancers and chronic infection, and discusses the epidemiology and molecular biology of infectious causes of cancers. It also explores the prevention and treatment of infection-related cancers, and brings pathogenic research to the forefront in the never-ending endeavor to understand how pathogens maneuver and negotiate in a complex environment, including the micro/macro- environment of the human host. Further, it highlights the urgent need for a concerted program to develop vaccines and other diagnosis and interventions that will eventually help prevent and treat infectious cancers, and decrease their burden on human populations. It offers graduate students and researchers a comprehensive overview of the infectious causes of cancers.
Category: Medical

Infection And Cancer Bi Directorial Interactions

Author : Michael R. Shurin
ISBN : 9783319206691
Genre : Medical
File Size : 77.26 MB
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This unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression. Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in response to therapy. The phenomenon of independent development of cancer and infection in the same host, known as comorbid cancer-infection progression, is explored. Understanding the complex pathways involved in the progression of infection and cancer will allow the prevention of the development of certain types of cancer, as well as advancing prophylactic anti-cancer vaccines. Readers of this work will discover innovative approaches for multidisciplinary projects, focusing on the design of original therapeutic modalities for cancer therapy. The book will therefore be particularly valuable to scholars interested in cancer immunology and researchers and clinicians in the field of basic and applied immunobiology and microbiology.
Category: Medical