Agents Of Bioterrorism

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Agents Of Bioterrorism

Author : Geoffrey Zubay
ISBN : 9780231518130
Genre : History
File Size : 65.92 MB
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This new work offers a clear and thorough account of the threats posed by bioterrorism from the perspective of biologists. The authors examine thirteen disease-causing agents, including those responsible for anthrax, the plague, smallpox, influenza, and SARS. Each chapter considers a particular pathogen from the standpoint of its history, molecular biology, pathology, clinical presentation, diagnosis, weaponization, and defenses. The book also examines strategies for making vaccines and protecting the population in a bioterror attack.
Category: History

Defence Against Bioterrorism

Author : Vladan Radosavljevic
ISBN : 9789402412635
Genre : Science
File Size : 26.3 MB
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This volume is based on a multidisciplinary approach towards biological and chemical threats that can, and have been previously used in bioterrorism attacks around the globe. Current knowledge and evidence-based principles from the fields of synthetic biology, microbiology, plant biology, chemistry, food science, forensics, tactics, infective medicine, psychology and others are compiled to address numerous aspects and the complexity of bioterrorism attacks. The main focus is on biological threats, especially in the context of synthetic biology and its emerging findings that can be observed as possible threat and tool. The book examines microorganisms and their possible use in forensics, i.e. as possible detection tool that could enable fast and precise detection of possible treats. A number of plant derived components are also discussed as possible agents in bioterrorism attacks, and in relation to infectious disease pathology. Another integral part is food safety, especially in terms of large food supply chains, like airline caterings, institutionalized kitchens etc. Food can be observed as a possible mean of delivery of various agents (biological and chemical) for bioterrorism attacks. Steps on how to recognize specific critical points in a food supply chain, along with proposed corrective activities are discussed. Examples from around the globe, along with the methodological approach on how to differentiate bioterrorism attacks from other epidemics are provided. However, epidemics are also discussed in the context of migrations, with the special emphasis on the current refugee migrations that affect not only Europe, but also the United States. The book will be of interest to experts from various fields of science as well as professionals working in the field. The book encompasses examples and tools developed for easier, more specific, and faster detection of possible bioterrorism treats, along with proposed actions for some aspects of a bioterrorism attack.
Category: Science

Bioterrorism And Infectious Agents

Author : I.W. Fong
ISBN : 1441912657
Genre : Medical
File Size : 42.33 MB
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Compiled by two leading experts in the field, this volume provides a concise, timely, and authoritative review of some of the most problematic infections of the new century. It presents issues and new ideas for preventing and controlling infectious diseases.
Category: Medical

Bioterrorism

Author : J. V. Borrelli
ISBN : 1600211801
Genre : Political Science
File Size : 27.59 MB
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A bioterrorism attack is the deliberate release of viruses, bacteria, or other germs (agents) used to cause illness or death in people, animals, or plants. These agents are typically found in nature, but it is possible that they could be changed to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Biological agents can be spread through the air, through water, or in food. Terrorists may use biological agents because they can be extremely difficult to detect and do not cause illness for several hours to several days. Some bioterrorism agents, like the smallpox virus, can be spread from person to person and some, like anthrax, can not. This new book presents new analyses on the prevention of, preparedness for and protection from.
Category: Political Science

Bioterrorism And Biocrimes

Author : W. Seth Carus
ISBN : 1410100235
Genre : Political Science
File Size : 88.61 MB
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The working paper is divided into two main parts. The first part is a descriptive analysis of the illicit use of biological agents by criminals and terrorists. It draws on a series of case studies documented in the second part. The case studies describe every instance identifiable in open source materials in which a perpetrator used, acquired, or threatened to use a biological agent. While the inventory of cases is clearly incomplete, it provides an empirical basis for addressing a number of important questions relating to both biocrimes and bioterrorism. This material should enable policymakers concerned with bioterrorism to make more informed decisions. In the course of this project, the author has researched over 270 alleged cases involving biological agents. This includes all incidents found in open sources that allegedly occurred during the 20th Century. While the list is certainly not complete, it provides the most comprehensive existing unclassified coverage of instances of illicit use of biological agents.
Category: Political Science

Bioterrorism And Infectious Agents

Author : I.W. Fong
ISBN : 1441912665
Genre : Medical
File Size : 73.10 MB
Format : PDF
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Compiled by two leading experts in the field, this volume provides a concise, timely, and authoritative review of some of the most problematic infections of the new century. It presents issues and new ideas for preventing and controlling infectious diseases.
Category: Medical

Clinical Guide To Bioweapons And Chemical Agents

Author : Vincent Friedewald
ISBN : 1846287871
Genre : Medical
File Size : 67.8 MB
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The book will assist in the new public health response to the threats from bioterrorism and other public health disease by combining established principles of disease management protocols with effective differential diagnosis algorithms. Although no single approach answers all of the challenges confronting our public health system, this book fulfills many of the requirements. The author has collated the current diagnostic criteria for all health-related bioterrorist threats and other public health disorders. The book represents the print version of this project and is intended to be a quick reference for the busy clinician.
Category: Medical

Bioterrorism Preparedness

Author : Nancy Khardori
ISBN : 9783527607730
Genre : Science
File Size : 20.54 MB
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Meeting the acute need for a book determining the crucial elements of bioterrorism preparedness, this is a global perspective of the history and current concepts for bioterrorism, integrating the legal, medical, scientific and public health strategies. It furthermore discusses the role of WHO and international health regulations for bioterrorism preparedness. For microbiologists, epidemiologists, biotechnologists, public health agencies, and pharmaceutists.
Category: Science

Animal Models For Assessing Countermeasures To Bioterrorism Agents

Author : National Research Council
ISBN : 9780309219099
Genre : Science
File Size : 73.85 MB
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The Transformational Medical Technologies (TMT) has been a unique component of the U.S. Department of Defense (DoD) medical biodefense efforts since 2006. Its mission is to advance countermeasure research and development in support of the broader goal of the DoD to protect warfighters from emerging infectious diseases and future genetically engineered biological weapons. The TMT, using advanced science and technology approaches, focused on the development of roadspectrum countermeasures that target common host and pathogen pathways or enhance the host's immune response. Many of these pathogens are lethal or cause such debilitating diseases in humans that it is ethically inappropriate to test the efficacy of these countermeasures in human volunteers. In lieu of human participants, these products may be tested in animals and approved for human use under the provisions of the Food and Drug Administration (FDA)'s 2002 Animal Rule. The reliance on animal models for the development and licensure of medical countermeasures against biothreats is challenging for a number of reasons. The ad hoc Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents prepared a consensus report that would address the challenges stemming from developing and testing medical countermeasures against biothreat agents in animal models. Animal Models for Assessing Countermeasures to Bioterrorism Agents evaluates how well the existing TMT-employed or candidate animal models reflect the pathophysiology, clinical picture, and treatment of human disease as related to the agents of interest. The report addresses the process and/or feasibility of developing new animal models for critical biodefense research, placing emphasis on the need for a robust and expeditious validation process in terms of the FDA's Animal Rule. The report also evaluates alternatives to the use of animal models based on the premise of the Three Rs.
Category: Science

Detection Of Biological Agents For The Prevention Of Bioterrorism

Author : Joseph Banoub
ISBN : 9789048198795
Genre : Science
File Size : 49.84 MB
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The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.
Category: Science

Overcoming Challenges To Develop Countermeasures Against Aerosolized Bioterrorism Agents

Author : National Research Council
ISBN : 9780309102117
Genre : Political Science
File Size : 67.55 MB
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The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies--including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)--be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.
Category: Political Science

Countering Bioterrorism

Author : National Research Council
ISBN : 9780309086073
Genre : Political Science
File Size : 64.27 MB
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The attacks of September 11 and the release of anthrax spores revealed enormous vulnerabilities in the U.S. public-health infrastructure and suggested similar vulnerabilities in the agricultural infrastructure as well. The traditional public health response-surveillance (intelligence), prevention, detection, response, recovery, and attribution-is the paradigm for the national response not only to all forms of terrorism but also to emerging infectious diseases. Thus, investments in research on bioterrorism will have enormous potential for application in the detection, prevention, and treatment of emerging infectious diseases that also are unpredictable and against which we must be prepared. The deciphering of the human genome sequence and the complete elucidation of numerous pathogen genomes, our rapidly increasing understanding of the molecular mechanisms of pathogenesis and of immune responses, and new strategies for designing drugs and vaccines all offer unprecedented opportunities to use science to counter bioterrorist threats. But these same developments also allow science to be misused to create new agents of mass destruction. Hence the effort to confront bioterrorism must be a global one. Countering Bioterrorism makes the following recommendations: Recommendation 1: All agencies with responsibility for homeland security should work together to establish stronger and more meaningful working ties between the intelligence, S&T, and public health communities. Recommendation 2: Federal agencies should work cooperatively and in collaboration with industry to develop and evaluate rapid, sensitive, and specific early-detection technologies. Recommendation 3: Create a global network for detection and surveillance, making use of computerized methods for real-time reporting and analysis to rapidly detect new patterns of disease locally, nationally, and ultimately- internationally. The use of high-throughput methodologies that are being increasingly utilized in modern biological research should be an important component of this expanded and highly automated surveillance strategy. Recommendation 4: Use knowledge of complex biological patterns and high-throughput laboratory automation to classify and diagnose infections in patients in primary care settings. Recommendation 5: USDA should create an agency for control and prevention of plant disease. This agency should have the capabilities necessary to deal effectively with biothreats.
Category: Political Science

Biological Warfare

Author : Don Nardo
ISBN : 9781420502558
Genre : Young Adult Nonfiction
File Size : 37.87 MB
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Biological warfare, bioterrorism, and germ weapons use disease producing agents such as bacteria or viruses as weapons toward people, animals, and plants. This critical resource helps students to investigate issues related to biological warfare. Readers will learn about biological agents and their harmful effects, the threat of existing bioweapons programs, and how countries are building up defenses against biological attacks.
Category: Young Adult Nonfiction

Bioterrorism Agents

Author : Jacob Casper
ISBN : OCLC:48705904
Genre : Animals
File Size : 71.22 MB
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Category: Animals

Bioterrorism

Author : Ernest P. Chiodo M.D. J.D M.P.H M.S. M.B.A. C.I.H.
ISBN : 9781479784325
Genre : Science
File Size : 46.61 MB
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Bioterrorism is a book that provides an overview of agents that may be used in acts of biological, chemical, and radiological terrorism. The material is presented at a level understandable to the layman. The first section of the book provides an overview of the types of technical experts that may be of help in preparing for and responding to acts ofbiological, chemical, and radiological terrorism. The second section discusses various biological agents of terrorism. The third section discusses chemical terrorism agents. The fourth section is concerned with radiological agents of terror. The fifth section discusses technical issues that are of importance in understanding biological, radiological, and chemical terrorism. The final section discusses legal issues of concern in biological, radiological, and chemical terrorism.
Category: Science

Biosecurity And Bioterrorism

Author : Jeffrey Ryan
ISBN : 9780128020579
Genre : Political Science
File Size : 68.8 MB
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Biosecurity and Bioterrorism, Second Edition, takes a holistic approach to biosecurity, with coverage of pathogens, prevention, and response methodology. It addresses these hazards in the context of vulnerability assessments and the planning strategies government and industry can use to prepare for and respond to such events. The book is organized into four thematic sections: Part I provides a conceptual understanding of biowarfare, bioterrorism and the laws we have to counteract this; Part II investigates known bioagents and the threat from emerging diseases; Part III focuses on agricultural terrorism and food security; and Part IV outlines international, US, and local initiatives for biodefense and biosecurity. Case studies illustrate biodefense against both intentional terrorism and natural outbreaks. Covers emerging threats of pandemic influenza, antibiotic resistant strains of bacterial pathogens, and severe respiratory diseases caused by novel viruses Offers increased international coverage, including initiatives to counter biological weapons and threats, and food security Updated throughout with latest protocols for dealing with biological threats and new case studies Includes online instructor ancillaries - PowerPoint lecture slides, test questions, and an instructor manual, for increased classroom functionality
Category: Political Science